Advancing oligonucleotide therapeutics from translational science to implementation.
GTOS 2027 brings together researchers, clinicians, industry, regulators, patient-linked stakeholders, and translational infrastructure experts to accelerate the responsible development of oligonucleotide therapeutics for rare and ultra-rare diseases.
About GTOS
GTOS is a focused translational symposium designed to connect German and international expertise in oligonucleotide therapeutics for rare diseases. The symposium broadly addresses scientific discovery, preclinical and clinical translation, biomarker strategies, regulatory development, implementation pathways and enabling infrastructure across rare disease areas.
GTOS 2027 will place a particular focus on rare and ultra-rare neurological diseases, highlighting current opportunities, challenges and translational approaches in this field.
Science
Oligonucleotide modalities, mechanisms, delivery, biomarkers.
Translation
Preclinical models, trial readiness,
clinical strategy.
Implementation
Regulation, ethics, infrastructure,
access and real-world pathways.
Committee
Established scientific and
organizational committee.
Heidelberg
Christian Schaaf
Rebecca Schüle
x
Sabrina Stängle
Tübingen
Holm Graeßner
Holger Lerche
Matthis Synofzik
Charlotte Kogel
Munich
Holger Prokisch
Matias Wagner
x
Irene Flavia Ferro
Cologne
Hormos Dafsari
Anne Koy
Emil Schober
Wednesday
14 Apr
Day 1
Pre-symposium workshops & opening
Registration
Industry-sponsored pre-symposium
workshops
Academia-initiated workshops
Opening welcome
Opening keynote: Translational state of the art in oligonucleotide therapeutics for rare neurological disease
Welcome reception, poster setup, and networking with exhibitors and poster presenters
Thursday
15 Apr
Day 2
Scientific & translational foundations
Session 1: Disease translation
– indication and unmet-need oriented
Session 2: Preclinical translation
– strategy, method and problem oriented
Session 3: Clinical translation
– strategy, method and problem oriented
Flash poster talks I
Curated industry showcase
Poster session and networking reception
Friday
16 Apr
Day 3
Implementation of ASO treatments
Session 4: Implementing ASO treatments for ultra-rare neurological diseases in the named-patient setting
Session 5: Regulatory and HTA development for individualized therapies in ultra-rare disease
Session 6: Building translational infrastructure in Germany
Session 7: Learning from other fields, countries, and modalities
Flash poster talks II / best abstracts
Speakers
Full Speaker announcements coming soon.
Richard S. Finkel, MD
St. Jude Children’s Research Hospital
United States Of America
Steve Petrou, PhD
Praxis Precision Medicines
Australia
Hayan Zhou, MD, PhD
University College London
United Kingdom
Prof. Andreas Brunklaus
Royal Hospital for Children, Glasgow
United Kingdom
Posters
Abstract submission opens 01.09.2026.
Categories for Poster Submissions
Venue & Travel
GTOS 2027 will take place at Bürgerhaus Heidelberg, Germany. The venue offers a central and accessible setting for the symposium, with convenient connections to hotels, restaurants, public transport and Heidelberg’s academic and clinical institutions. Heidelberg is also a leading academic, medical and research location with a strong translational science environment.
Bürgerhaus
Gadamerplatz 1
69115 Heidelberg
Deutschland
Sponsors
Support a focused translational meeting connecting oligonucleotide science, rare disease expertise, clinical implementation, regulatory development, and industry innovation.
GTOS offers sponsors and exhibitors a highly targeted environment to engage with academic investigators, clinicians, translational researchers, regulatory experts, manufacturing and analytics specialists, and selected patient-centered implementation stakeholders
Lead Partner
- Top-tier branding
- Premium exhibition table
- 4 registrations
- Curated industry showcase slot
- Option to support one pre-symposium workshop
- Acknowledgment at opening
Principal Sponsor
- Prominent branding
- Exhibition table
- 3 registrations
- Curated showcase slot
- Option to support networking or poster element
Supporting Sponsor
- Logo visibility
- Tabletop exhibition
- 2 registrations
- Acknowledgement in sponsor materials and on-site slides.
Exhibitor
- Logo visibility
- Tabletop exhibition
- 1 registration
- Listing in exhibitor and sponsor materials.